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Frequently Asked Questions and Scientific Studies

Age

 years
Gender MaleFemale
Race BlackNon-Black
Ethnicity
Ethnicity
Smoker YesNo

Heart risk is reversed after 5-10 years of no smoking

Smoker
Smoker
Diabetes YesNo
Diabetes

Systolic Blood Pressure

 mmHg

Enter present blood pressure regardless of treatment

120 mmHg is used for baseline risk

On treatment for BP YesNo

Click YES if taking blood pressure medication

Only applies if SBP is greater than 120 mmHg

On lipid-lowering treatment YesNo

Click YES if taking lipid-lowering medication

On antithrombotic treatment YesNo

Click YES if taking antiplatelet/anticoagulant medication

Total Cholesterol

 mmol/L
 mg/dL

Cholesterol should be prior to drug treatment

3 mmol/L is used for baseline risk.
Click to change to mg/dL.

116 mg/dL is used for baseline risk.
Click to change to mmol/L.

HDL Cholesterol

 mmol/L
 mg/dL

HDL should be prior to drug treatment

1.3 mmol/L is used for baseline risk.

50 mg/dL is used for baseline risk.

Family History of Heart YesNo

Angina or heart attack in a 1st degree relative < 60 yrs

Chronic Kidney Disease YesNo

CKD status is not part of the risk algorithm but is used for calculating the benefit of certain therapies

Atrial Fibrillation YesNo
Deprivation Quintile

This socioeconomic deprivation index can be determined by answering eight questions. For detailed information, see page two of the NZDep2013 brief flyer or visit the website.

Rheumatoid Arthritis YesNo

Height

 cm
 in

Weight

 kg
 lbs
BMI

BMI of 25 kg/m2 for baseline risk

Family History of Heart Disease

%

The amount of additional risk (relative increase in risk) conferred from a family member to a patient depends on: (1) how close a relative, (2) age of a relative, (3) number of affected family members.

If mother (< 65 yrs) increase risk 60%

If father (< 55 yrs) increase risk 75%

Relative Benefit:  
0

Benefit often has nothing to do with the effect on the surrogate marker. At present, you can only select one intervention at a time.

  • Physical Activity
  • Mediterranean Diet vs Low fat
  • Vitamin/Omega-3 supplements
  • BP meds (not atenolol/doxazosin)
  • Low-mod intensity statins
  • High intensity statins
  • Fibrates
  • Niacin
  • Ezetimibe
  • Metformin
  • Sulfonylureas
  • Insulins
  • Glitazones
  • GLPs
  • DPP-4s
  • Meglitinides
  • SGLT2
  • Smoking Cessation
  • ASA
Benefit Estimate Details

Risk Time Period

10 years
No event
Total with an event
Number who benefit from treatment
NNT % Number needed to treat
Baseline events using baseline factors alone
Additional events “caused” by risk factors

As with all risk calculators, calculated risk numbers are +/- 5% at best.

.

See the QRISK®2 disclaimer for more information.

Dr Shukla

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